Kalel Mullings surged 2 yards for a touchdown run on fourth down with 37 seconds left, lifting No. 18 Michigan to a 27-24 win over No. 11 Southern

The senior running back turned in a career day for a second straight week, rushing for 159 yards and two touchdowns in a 27-24 win over No. 11 USC to open Big Ten play on Saturday. Michigan improves to 3-1 to start the season under new coach Sherrone Moore.

The Wolverines grinded out a win over the Trojans, plus the rest of the weekend’s most notable winners and losers.

The lineage of quarterbacks developed under USC coach Lincoln Riley makes him one of the most respected offensive minds in college football, but the No. 18 Wolverines beat the Trojans in the Big House without much of a need for a traditional quarterback. Its ability to dictate the game in the trenches was in stark contrast to the Texas loss.

For coach Sherrone Moore and the No. 17 Wolverines, Saturday's game will be a chance to reassert themselves as a legitimate threat to make the 12-team College Football Playoff after a blowout 31-12 loss to Texas earlier this month.

Pretty much every college football analyst expected Michigan football to lose to USC on Saturday, but they play the games for a reason. With Alex Orji at the helm as the starting quarterback for the first time,

The No. 18 Michigan Wolverines came away with an upset over the No. 11 USC Trojans in Ann Arbor, 27-24. More news: Former Alabama HC Nick Saban Throws Massive Shade at Rival SEC Program It was a back-and-forth affair that lacked zero action throughout the 60-minute contest.

Here's what to watch as No. 11 USC heads to Ann Arbor, Mich., to take on No. 18 Michigan on Saturday at 12:30 p.m. PDT. The game will air on CBS.

Get tickets to see the USC Trojans take on the Michigan Wolverines in Ann Arbor, Saturday, Sept. 21, at 3:30pm. SeatGeek, Stubhub, Vivid Seats and Ticketmaster have tickets for the afternoon game with ticket prices starting around $38.