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WEB1 day ago · Explore BioTechniques. A world leader in life science method research news. ISSN (print): 0736-6205 | ISSN (online): 1940-9818.
DNA Methylation Sequencing | Epigenetics - BioTechniques
WEBOct 15, 2018 · Methylation enrichment sequencing. Methylated DNA immunoprecipitation sequencing (MeDIP-seq) and methylated DNA binding domain sequencing (MBD-seq) both act by enriching the methylated regions before sequencing. When used alone these avoid the potentially damaging effects of bisulfite. MeDIP-sequencing involves fragmenting the DNA into various ...
For authors - BioTechniques
WEBContact Senior Editor, Tristan Free, to find out more about digital opportunities with BioTechniques, or check out this information on how to spread the word about your article. Answers to any questions authors may have about the BioTechniques journal. Including fees, forms, templates, author guidelines and how to submit an article.
Two minutes with: Yuri Nikolsky on immunosequencing
WEBMay 6, 2020 · Yuri Nikolsky. I have PhD in molecular genetics from Moscow State University (Russia). I moved to the University of Chicago in 1993 as a researcher and then I went to the Chicago Booth business school (both IL, USA). As a student I began working on startups – I co-founded Integrated Genomics (IL, USA) in 1997 and GeneGo in 2001.
What is Western Blotting? The Story of the Western Blot
WEBJul 18, 2018 · The technique involves the identification and characterization of DNA-binding proteins using DNA probes (Southern) and protein blotting (western) and was first described in 1980. This method was published before the western blot. Yet, it still alludes to it in its name, reaffirming the popularity of the western blot.
Western Blotting Summary - BioTechniques
WEBWestern blotting (or immunoblotting) is a well-established biochemical technique that detects specific proteins in complex samples and has applications from basic research to the diagnosis of infectious diseases. Western blotting can be used to determine quantity, molecular weight and post-translational modifications of proteins and can ...
Protecting the powerhouse of the cell - BioTechniques
WEBJan 11, 2019 · The mitochondria, often labeled the powerhouse of the cell, are the organelle responsible for energy production within the cell. Playing an important role in cellular respiration, the mitochondria are the main location for ATP production. They also make proteins essential for DNA metabolism such as the iron-sulfur family of proteins.
How Early Life Thrived Without Oxygen - BioTechniques
WEBJan 11, 2017 · For a couple billion years, our planet’s gassy shell contained water vapor, nitrogen, carbon monoxide, and carbon dioxide. During these eons, water vapor condensed and formed vast oceans—flowing nurseries with the right conditions for early life. Even so, the absence of free oxygen in the air would not support life as we see it today.
Five Top Biomedical Trends in 2021 - BioTechniques
WEBJan 8, 2021 · Company news Diagnostics and preclinical General interest Opinion. From multi-omics and big data to ‘lights out science’ – SCIEX’s Tom Knapman predicts the top five biomedical trends in 2021. This year has been unprecedented in so many ways. Despite the obvious unfortunate events, there have …
Crocodile Teeth Have Thin Enamel - BioTechniques
WEBAug 15, 2019 · Researchers have demonstrated that crocodile teeth have much thinner enamel layers than humans and other hard-biting species. It’s well known that crocodiles possess one of the most powerful bites in the animal kingdom. However, the actual structure and proportion of dental tissues in crocodiles’ teeth is relatively unexplored – …